ACC Opens Enrollment for New NCDR Renal Denervation Module Developed with Smith Center

The BIDMC Smith Center for Outcomes Research is pleased to announce that the American College of Cardiology’s NCDR Renal Denervation (RDN) Module, developed in partnership with the Smith Center, is now open for enrollment.

The launch of the RDN Module within the National Cardiovascular Data Registry (NCDR) environment marks the beginning of a formal collaboration between the Smith Center and the ACC for the advancement of hypertension therapy research.

What started as a small-scale multisite Registry created and operated by the Smith Center is now the foundation for an NCDR-housed research database for the collection of longitudinal clinical data on RDN patients, addressing the need for real-world data on the longevity and efficacy of renal denervation.

“The NCDR Renal Denervation Module represents an important milestone for the field,” says Dr. Eric Secemsky, Director of Vascular Intervention at BIDMC and co-founder of the Smith Center RDN Registry. “Real-world data are essential to understanding how renal denervation performs outside of clinical trials. By expanding this registry through the ACC’s NCDR platform, we will be able to generate high-quality evidence that helps clinicians optimize patient selection, procedural practice, and long-term outcomes.”

Dr. Anna Krawisz, hypertension specialist and co-founder of the Smith Center RDN Registry with Dr. Secemsky, adds, “This initiative feels especially important in the context of both the increasing prevalence of hypertension and the wider adoption of RDN in the U.S. Patients with hypertension and those who manage their care stand to benefit immensely from the breadth of data that this registry will collect.”

The NCDR Renal Denervation Module is expected to support a broad range of research initiatives, including studies focused on patient selection, procedural outcomes, health disparities, quality improvement and long-term effectiveness. Insights generated through the partnership will help inform best practices and contribute to the growing body of evidence surrounding renal denervation therapy.

“The NCDR Renal Denervation Module reflects our shared commitment to advancing cardiovascular care through high-quality clinical data and research,” says ACC’s NCDR Oversight Committee Chair Frederic S. Resnic, MD, MSc, FACC. “As renal denervation becomes more widely adopted, this partnership with the Smith Center will create a robust platform for collecting real-world data and provide critical insights that support best practices, better equipping clinicians to make informed treatment decisions and improve outcomes for patients with hypertension.”

RDN-performing sites interested in participating in the NCDR RDN Module are encouraged to contact ACC on their website for more information about enrollment. If your site already participates in an NCDR registry, they are able to enroll in the RDN Module at no extra cost.